. Author manuscript; available in PMC: 2021 Jun 1.

Published in final edited form as: Osteoporos Int. 2020 Jan 14;31(6):1105–1114. doi: 10.1007/s00198-019-05275-1

Table 3.

Average yearly percent change in femoral neck width and the strength indices from baseline (95% CI) by study group arm and year of follow-up

	Active (Vitamin D₃)			Placebo
Measure	1-year	2-year	3-year	1-year	2-year	3-year
Femoral neck BMD (g/cm2)	0.77 (− 0.04,1.59)	−0.5 (− 1.3,0.29)	−1.28 (−2.2,− 0.37)	−0.4 (− 1.13,0.32)	−1.27 (−2.1,− 0.44)	−2.01 (−2.99,− 1.04)
Femoral Neck width (cm)	0.66 (− 0.26,1.57)	1.05 (0.16,1.94)	1.12 (0.26,1.99)	1.14 (0.39,1.89)	1.15 (0.08,2.22)	1.51 (0.58,2.44)
Compression Strength Index, (g/kg*m)	2.1 (0.59,3.61)	0.95 (− 0.97,2.88)	1.46 (− 0.31,3.23)	1.73 (0.3,3.16)	1.4 (− 0.35,3.15)	1.98 (− 0.1,4.06)
Bending Strength Index, (g/kg*m)	2.99 (0.77,5.21)	2.49 (− 0.13,5.12)	2.43 (0.08,4.78)	3.1 (0.97,5.22)	2.71 (− 0.05,5.47)	3.6 (0.72,6.48)
Impact Strength Index, (g/kg*m)	2.26 (0.65,3.86)	0.99 (− 0.96,2.94)	2.1 (0.27,3.92)	2.38 (0.89,3.88)	2.2 (0.37,4.04)	2.87 (0.67,5.07)

BMD – bone mineral density; CI – confidence interval