Supplemental Table 2.
Final Cox Proportional Hazards Model of risk factors for death or Intubation Among Patients With COVID-19
| Characteristics | Death or intubation/n at risk (%) | Hazard ratio (95% CI) |
|
|---|---|---|---|
| Full model | Final model | ||
| Famotidine | |||
| No | 332/1536 (22) | Reference | Reference |
| Yes | 8/84 (10) | 0.43 (0.21–0.86) | 0.42 (0.21–0.85) |
| Age (y) | |||
| <50 | 19/333 (5.7) | Reference | Reference |
| 50–65 | 75/514 (15) | 2.94 (1.77–4.89) | 3.03 (1.83–5.03) |
| >65 | 246/773 (32) | 7.51 (4.66–12.1) | 7.68 (4.79–12.3) |
| Sex | |||
| Male | 197/909 (22) | Reference | — |
| Female | 143/711 (20) | 1.11 (0.89–1.38) | |
| Race/ethnicity | |||
| Hispanic | 129/626 (21) | Reference | — |
| White, non-Hispanic | 84/355 (24) | 0.99 (0.75–1.31) | |
| Black, non-Hispanic | 59/340 (17) | 0.82 (0.60–1.13) | |
| Other | 68/299 (23) | 1.14 (0.85–1.53) | |
| Body mass index, kg/m2 | |||
| <25.0 | 86/310 (28) | Reference | — |
| 25.0–29.9 (overweight) | 92/418 (22) | 0.88 (0.65–1.18) | |
| ≥30 (obese) | 89/456 (20) | 0.97 (0.72–1.31) | |
| Not recorded | 73/436 (17) | 0.67 (0.49–0.92) | |
| Comorbidities | |||
| Diabetes | 72/335 (21) | 1.02 (0.75–1.37) | — |
| Hypertension | 94/457 (21) | 0.72 (0.54–0.97) | 0.74 (0.58–0.94) |
| CAD | 24/118 (20) | 0.77 (0.49–1.21) | — |
| Heart failure | 24/92 (26) | 1.06 (0.67–1.67) | — |
| ESRD or CKD | 33/141 (23) | 1.16 (0.77–1.75) | — |
| Chronic pulmonary disorders | 29/122 (24) | 1.29 (0.87–1.93) | — |
| Initial oxygen requirement | |||
| Room air | 52/403 (13) | Reference | — |
| Nasal canula | 155/716 (22) | 1.60 (1.17–2.19) | 1.63 (1.19–2.24) |
| Non-rebreather | 133/501 (27) | 2.48 (1.79–3.44) | 2.39 (1.73–3.29) |
CAD, coronary artery disease; CKD, chronic kidney disease; ESRD, end-stage renal disease.