Table 2.
Comparison of chosen parameters (means ± SD) in the groups with different probability of PH on echocardiography
| Parameter | Group A (low PH probability) | Group B (increased PH probability) | p |
|---|---|---|---|
| Age (years) | 43.8 ± 12.2 | 57.6 ± 12.1 | 0.0000006 |
| Smoking (pack-years) | 6.9 ± 14.0 | 17.8 ± 21.8 | 0.0043 |
| 6MWD (m) | 583.1 ± 111.6 | 478.2 ± 109 | 0.0000204 |
| Sat 0 (%) | 96.6 ± 2.3 | 95.8 ± 1.9 | 0.00227 |
| Sat 6 (%) | 93.4 ± 5.2 | 89.1 ± 7.0 | 0.000566 |
| Desaturation (%) | 3.3 ± 3.9 | 6.7 ± 5.7 | 0.0013 |
| FEV1%FVC | 78.5 ± 6.3 | 75.8 ± 9.3 | 0.1746 |
| FVC (% pred) | 94.5 ± 22.7 | 95.0 ± 21.3 | 0.9126 |
| TLC (% pred) | 96.0 ± 19.4 | 91.9 ± 21.9 | 0.3524 |
| DLCO (% pred) | 70.5 ± 20.8 | 54.8 ± 22.2 | 0.0005 |
| TLC/DLCO | 1.44 ± 0.6 | 1.86 ± 0.6 | 0.00001 |
| FVC/DLCO | 1.4 ± 0.45 | 1.82 ± 0.67 | 0.00001 |
| VC/DLCO | 1.43 ± 0.48 | 1.94 ± 0.68 | 0.00001 |
| NT-proBNP (pg/ml) | 58.4 ± 53.9 | 150.7 ± 300.7 | 0.019 |
DLCO diffusion lung capacity for carbon monoxide, FEV1 forced expiratory volume in one second, FVC forced vital capacity, 6MWD 6-min walk distance, NT-proBNP N-terminal brain natriuretic peptide, PH pulmonary hypertension, Sat0 baseline room air oxygen saturation, Sat6 sixth minute room air oxygen saturation, TLC total lung capacity, TLC/DLCO total lung capacity% predicted/diffusion lung capacity for carbon monoxide corrected for haemoglobin % predicted, FVC/DLCO forced vital capacity %predicted/diffusion lung capacity for carbon monoxide corrected for haemoglobin % predicted, VC/DLCO vital capacity %predicted/diffusion lung capacity for carbon monoxide corrected for haemoglobin % predicted