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. 2020 Mar 23;198(3):547–554. doi: 10.1007/s00408-020-00346-1

Table 4.

Optimal cut off values of different parameters for PH prediction

Parameter Cut off Specificity Sensitivity PPV NPV
Age (years) 53 0.85 0.76 0.79 0.81
Pack-years 1.75 0.69 0.61 0.58 0.71
6MWD (m) 507.5 0.76 0.63 0.68 0.72
Sat 0 (%) 96 0.76 0.68 0.69 0.75
Sat 6 (%) 93 0.75 0.65 0.67 0.73
Desaturation (%) 4 0.71 0.65 0.63 0.72
DLCO (% pred) 68 0.67 0.78 0.65 0.79
TLC/DLCO 1.67 0.92 0.65 0.87 0.77
NT-proBNP (pg/ml) 38 0.49 0.77 0.54 0.74

DLCO diffusion lung capacity for carbon monoxide, 6MWD 6-min walk distance, NT-proBNP N-terminal brain natriuretic peptide, PH pulmonary hypertension, Sat0 baseline room air oxygen saturation, Sat6 sixth minute room air oxygen saturation, TLC/DLCO total lung capacity% predicted/diffusion lung capacity for carbon monoxide corrected for haemoglobin % predicted