Table 4.
Pathways enriched for each mineral considering the gene expressions correlated to each one of them and the previously detected differentially expressed genes related to the same minerals in the same Nelore population.
| Ca | Cu | K | Mg | Na | P | S | Se | Fe | |
|---|---|---|---|---|---|---|---|---|---|
| AMPK signalling pathway | 3 | ||||||||
| Antigen processing and presentation | 1 | ||||||||
| Assembly of collagen fibrils and other multimeric structures | |||||||||
| Biosynthesis of unsaturated fatty acids | 1 | ||||||||
| Collagen biosynthesis and modifying enzymes | 2 | 2 | |||||||
| Collagen chain trimerization | 2 | 2 | 2 | 2 | |||||
| Collagen formation | 2 | ||||||||
| DAP12 interactions | 2 | ||||||||
| Degradation of the ECM | 2 | ||||||||
| ECM organization | 2 | 2 | 2 | 2 | 2 | 2 | |||
| ECM-receptor interaction | 1 | 3 | 3 | 3 | 3 | 1 | 1 | ||
| Fatty acid biosynthesis | 3 | ||||||||
| Fatty acid metabolism | 3 | ||||||||
| Fc gamma receptor (FCGR) dependent phagocytosis | 2 | ||||||||
| Focal adhesion | 1 | 1 | 1 | 1 | 1 | ||||
| G alpha (q) signalling events | 2 | ||||||||
| Herpes simplex infection | 1 | ||||||||
| Immune system | 2 | ||||||||
| Influenza A | 1 | ||||||||
| Innate immune system | 2 | ||||||||
| Integrin cell surface interaction | 2 | 2 | 2 | ||||||
| Measles | 1 | ||||||||
| Neutrophil degranulation | 2 | ||||||||
| Non-integrin membrane-ECM interactions | 2 | ||||||||
| O-glycosylation of TSR domain-containing proteins | 2 | ||||||||
| Phagosome | 1 | ||||||||
| PI3K-Akt signalling pathway | 1 | 1 | 1 | 1 | 1 | ||||
| Platelet activation | 1 | ||||||||
| PPAR signalling pathway | 1 | 1 | |||||||
| Prion disease | 3 | ||||||||
| Protein digestion and absorption | 1 | 3 | 3 | 3 | 3 | 1 | |||
| Signal transduction | 2 |
Pathways just enriched in previous works with a differential expression approach and the same Nelore population are represented by the number 1, pathways enriched in our correlated genes expression are represented by the number 2 and the pathways enriched both in previous work and in the correlated genes expressions are represented by the number 3. There were no enriched pathways for Zn.