Fig 3. Correlation network analysis of relative abundances of organisms (rpS3 genes) and relative abundance of IPL signatures.

The primary lipids were defined based on a direct correlation of their relative abundance with rpS3 gene abundance (Bonferroni-corrected p value < 0.005). Secondary lipids showed a significant correlation with primary lipids and are indicative of a biological connection between the lipids (e.g., lipids from microbial symbionts or co-correlated organisms). Unspecific lipids shared primary lipids with different organism assignment. Due to visual limitations only few IPL names are displayed in the figure; all organisms to lipid correlations are provided in Table 1, raw data can be accessed in Tables S4 and S5.