Table 1.
A summary of published cases of Clostridial osteomyelitis
| Paper | Clostridium species | Type of infection | No. of cases | Case details (where known) |
|---|---|---|---|---|
| Mormeneo Bayo et al. 2020 | Clostridium celerecrescens | Fracture related infection | 1 | 39F sustained bilateral open femoral fractures in road traffic accident |
| Tremp et al. 2020 | Clostridium spp. | Fracture related infection | 1 | 43F farmer stumbled over doorstep, sustained trimalleolar open fracture |
| Clostridium butyricum | Fracture related infection | 1 | 58F fell into cesspool, sustained bimalleolar fracture and soft tissue injury | |
| Vijayvargiya et al. 2019 | Clostridium paraputrificum | Septic arthritis and osteomyelitis | 1 | 86F native shoulder joint septic arthritis and osteomyelitis |
| Abusnina et al. 2019 | Clostrodium sporogenes | Osteomyelitis | 1 | 66F obese non-insulin dependent diabetic with pressure ulcer associated osteomyelitis |
| Hirai et al. 2017 | Clostridium hydrogeniformans | Fracture related infection | 1 | 18M sustained open right arm fracture in motorbike accident contaminated by drain contents |
| Perkins et al. 2017 | Clostridium sphenoides | Fracture related infection | 1 | 20M sustained open right radius and ulna fracture whilst wrestling, contaminated with soil. |
| Mutoh et al. 2015 | Clostridium innocuum | Osteomyelitis | 1 | 32M with ALL and pelvic osteomyelitis and bacteraemia, unclear source |
| Virot et al. 2015 | Clostridium tertium | Osteomyelitis | 1 | 40M ex soldier with osteomyelitis surrounding shrapnel in tibia |
| Ibnoulkhatib et al. 2012 | Clostridium spp. | Fracture related infection | 12 | Multiple cases of traumatic fracture, each with soil contamination |
| Mischnik et al. 2011 | Clostridium celerescens | Fracture related infection | 1 | 55M with peripheral vascular disease and a history of open tibial fracture |
| Taylor et al. 2010 | Clostridium argentinense | Fracture related infection | 1 | 34M with contaminated open fracture of right ulna and radius playing soccer |
| Jiang et al. 2009 | Clostridium glycolicum | Fracture related infection | 1 | 20F with open fracture of radius and ulna after a road vehicle accident |
| Tekaya et al. 2008 | Clostridium clostridiiforme | Vertebral osteomyelitis | 1 | |
| Kihiczak et al. 1999 | Clostridium septicum | Osteomyelitis | 1 | |
| Shetty et al. 1998 | Clostridium septicum | Osteomyelitis | 1 | |
| Scanlan et al. 1994 | Clostridium bifermentans | Osteomyelitis | 1 | 81M with oropharyngeal lymphoma, bacteraemia and multifocal osteomyelitis (T11-L5, sacrum and ribs) of unclear source |
| Spitzer et al. 1991 | Clostridium clostridiiforme | Osteomyelitis | 1 | |
| Brook et al. 1993 | Clostridium spp. | 'Bone infection' | 1 | |
| Neimkin et al. 1985 | Clostridium septicum | Osteomyelitis | 1 |