. 2020 May 21;10:8444. doi: 10.1038/s41598-020-65368-4

Table 2.

Relationship between the suprapatellar effusion area and the amount of change in the muscle mass of the lower extremity.

Dependent variable	Independent variable	Model	B	P	OR	95% CI
ΔMM_BL-1Y (kg)	Continuous value of Effusion area (mm²)	Crude	−0.0015	0.004^*		−0.0025	—	−0.0005
ΔMM_BL-1Y (kg)	Continuous value of Effusion area (mm²)	Adjusted	−0.0009	0.033^*		−0.0017	—	−0.0001
ΔMM_1Y-3Y (kg)	Continuous value of Effusion area (mm²)	Crude	0.0004	0.587		−0.0009	—	0.0016
ΔMM_1Y-3Y (kg)	Continuous value of Effusion area (mm²)	Adjusted	−0.0001	0.845		−0.0015	—	0.0013
Prevalence of SMML_BL-1Y	Cut-off: 30 mm²	Crude	1.412	0.047^*	4.105	1.018	—	16.563
	Cut-off: 30 mm²	Adjusted	1.895	0.045^*	6.653	1.046	—	42.301
	Cut-off: 90 mm²	Crude	1.828	0.007^*	6.222	1.638	—	23.629
	Cut-off: 90 mm²	Adjusted	3.071	0.003^*	21.561	2.779	—	167.265

Statistical analysis: generalized estimating equations, ^*p ≤ 0.05. Adjusted model is conducted by including the confounding of age, sex, BMI, KOOS pain scale, Kellgren-Lawrence grade, MM, and weekly exercise habit (all at baseline). B: regression coefficient; BL: baseline; MM: muscle mass; OR: odds ratio; P: P-value; SMML: severe muscle mass loss; 95% CI: 95% confident interval.