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. 2020 Mar 4;14(6):1479–1493. doi: 10.1038/s41396-020-0623-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — The MGEs including transposases (a), plasmid replication essential proteins (b), and prophage proteins (c) contents among selected strains with complete, incomplete or no CRISPR-Cas systems are shown. The contents were compared by calculating the numbers of each kind of MGEs per genome of each group. d The comparison of unique gene diversity value among B. cereus group strains. Unique gene diversity was compared by calculating the rate of unique genes per genome for all the selected genomes. The significance of the differences among samples was evaluated using two sample Wilcoxon–Mann–Whitney test at, p < 0.0001 (****) p < 0.001 (***), p < 0.01 (**) and p < 0.05 (*).