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. 2020 Mar 23;14(6):1600–1613. doi: 10.1038/s41396-020-0632-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Bootstrap values were based on 100 replicates, and only bootstrap values higher than 70% are shown with black circles. The accession number of each published protein is shown in parenthesis. The new GCDs recovered in our study are indicated with red stars. The published GCDs with functional validation by experimentation in the literature are indicated with green circles. Numbers of genes annotated as mobile genetic elements involved in horizontal gene transfer (HGT) on the same scaffolds with gcd genes are indicated with green bars outside the phylogenetic tree. Details on mobile genetic elements involved in HGT were provided in Table 2 and Table S7.