Skip to main content
. 2020 May 15;11:910. doi: 10.3389/fmicb.2020.00910

TABLE 3.

Characteristics of cefepime-resistant Salmonella Enteritidis donor strains and transconjugants.

Isolates Beta-lactamase gene No. of plasmids Size of plasmids harboring the blaCTX–M gene Replicon type Upstream of blaCTX–M Downstream of blaCTX–M MIC (μ g/mL)
CTX CAZ FEP
E. coli C600 <0.125 <0.125 <0.125
SH11G394 blaCTX–M–55, TEM, SHV 1 76.8 kb 256 32 32
SH11G394-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 16 2 2
SH11G405 blaCTX–M–55, TEM 1 76.8 kb 256 32 32
SH11G405-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 64 4 8
SH11G1338 blaCTX–M–55, TEM, SHV 1 76.8 kb 256 32 32
SH11G1338-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 64 4 8
SH11G1355 blaCTX–M–55, TEM, SHV 1 76.8 kb 256 32 32
SH11G1355-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 128 4 8
SH11G1371 blaCTX–M–55, TEM 1 76.8 kb 256 32 32
SH11G1371-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 64 8 8
SH12G565 blaCTX–M–55, TEM 1 76.8 kb 256 32 32
SH12G565-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 32 8 4
SH12G706 blaCTX–M–55, TEM 1 76.8 kb 256 32 32
SH12G706-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 32 4 4
SH13G961 blaCTX–M–55 1 76.8 kb 256 32 32
SH13G961-C* blaCTX–M–55 1 76.8 kb I1 ISEcp1 ORF-477 128 4 8
SH12G460 blaCTX–M–55, TEM, SHV 2 54.7 kb, 76.8 kb >512 64 32
SH12G460-C* blaCTX–M–55 1 76.8 kb FIIA, FIIB, FrepB ORF-477 32 4 4
SH12G514 blaCTX–M–55 1 104.5 kb 256 32 32
SH12G514-C* blaCTX–M–55 1 104.5 kb FrepB ORF-477 256 4 8
SH12G729 blaCTX–M–55, TEM, SHV, PSE, ACC 1 76.8 kb 256 32 32
SH12G729-C* blaCTX–M–55 1 76.8 kb FrepB ORF-477 32 4 2
SH12G1079 blaCTX–M–55, SHV 1 104.5 kb 256 32 32
SH12G1079-C* blaCTX–M–55, SHV 1 104.5 kb FIIA, FrepB ORF-477 16 4 2
SH12G1166 blaCTX–M–55, TEM, SHV 2 104.5 kb, >138.9 kb 128 16 32
SH12G1166-C* blaCTX–M–55 1 >138.9 kb N, FIIB, FrepB ORF-477 128 4 8
SH13G474 blaCTX–M–55, TEM, SHV 2 54.7 kb, 76.8 kb 256 32 32
SH13G474-C* blaCTX–M–55 1 76.8 kb FIIA, FIIB, FrepB ORF-477 64 4 4
SH13G990 blaCTX–M–55, SHV 2 54.7 kb, 104.5 kb 256 32 32
SH13G990-C* blaCTX–M–55 1 104.5 kb FIIA, FIIB, FrepB ORF-477 128 4 4
SH13G1032 blaCTX–M–55, SHV 1 76.8 kb 256 32 32
SH13G1032-C* blaCTX–M–55 1 76.8 kb FIIA, FIIB, FrepB ORF-477 64 4 4
SH13G1838 blaCTX–M–55, SHV 1 138.9 kb 256 32 32
SH13G1838-C* blaCTX–M–55 1 138.9 kb N, FrepB ORF-477 128 4 4
SH13G1868 blaCTX–M–55, SHV 1 76.8 kb 256 32 32
SH13G1868-C* blaCTX–M–55 1 76.8 kb FrepB ORF-477 16 0.5 2
SH13G1882 blaCTX–M–55 1 76.8 kb 256 32 16
SH13G1882-C* blaCTX–M–55 1 76.8 kb FrepB ORF-477 64 4 4
SH13G1958 blaCTX–M–55, SHV, ACC 2 54.7 kb, 138.9 kb 256 32 32
SH13G1958-C* blaCTX–M–55 1 138.9 kb FIIA, FIIB, FrepB ORF-477 64 4 4
SH14G065 blaCTX–M–55, SHV, ACC 1 76.8 kb 256 32 32
SH14G065-C* blaCTX–M–55 1 76.8 kb FrepB ORF-477 128 4 4
SH14G169 blaCTX–M–55, SHV, ACC 2 54.7 kb, 104.5 kb 256 32 32
SH14G169-C* blaCTX–M–55 1 104.5 kb FIIA, FIIB, FrepB ORF-477 128 4 4
SH14G548 blaCTX–M–55, SHV, ACC 2 54.7 kb, 76.8 kb 256 32 32
SH14G548-C* blaCTX–M–55 1 76.8 kb FIIA, FIIB, FrepB ORF-477 128 4 8
SH14G1579 blaCTX–M–55 2 54.7 kb, 104.5 kb 256 32 32
SH14G1579-C* blaCTX–M–55 1 104.5 kb FIIA, FIIB, FrepB ORF-477 64 4 4
SH13SF278 blaCTX–M–55, SHV 2 54.7 kb, 138.9 kb 256 32 32
SH13SF278-C* blaCTX–M–55 1 138.9 kb FrepB ISEcp1 ORF-477 128 8 8
SH14SF008 blaCTX–M–55, SHV 2 54.7 kb, 104.5 kb ∼ 138.9 kb 256 32 16
SH14SF008-C* blaCTX–M–55 2 54.7 kb, 104.5 kb ∼ 138.9 kb FIIA, FIIB, FrepB ORF-477 128 4 2
SH12G402 blaCTX–M–3, TEM, SHV, PSE 1 76.8 kb 128 8 32
SH12G402-C* blaCTX–M–3, TEM 1 76.8 kb L/M ISEcp1 ORF-477 32 1 8
SH14G1019 blaCTX–M–55, TEM, SHV 2 54.7 kb, 104.5 kb >512 512 128
SH14G1019-C* blaCTX–M–55 1 104.5 kb FIIA, FIIB, FrepB ISEcp1 ORF-477 128 4 8
SH14G1041 blaCTX–M–55, TEM, SHV 1 76.8 kb >512 512 64
SH14G1041-C* blaCTX–M–55 1 76.8 kb FrepB ISEcp1 ORF-477 32 2 2
SH12G477 blaCTX–M–15, TEM 1 104.5 kb 256 32 32
SH12G477-C* blaCTX–M–15 1 104.5 kb I1 ISEcp1 ORF-477 64 4 8
SH12G1178 blaCTX–M–123, TEM 1 104.5 kb ∼ 138.9 kb 512 64 32
SH12G1178-C* blaCTX–M–123 1 104.5 kb ∼ 138.9 kb I1 ISEcp1 ORF-477 128 8 8
SH12G465 blaCTX–M–64, SHV 1 76.8 kb >512 32 32
SH12G465-C* blaCTX–M–64 1 76.8 kb - ISEcp1 ORF-477 64 8 8
SH12G1019 blaCTX–M–64, TEM, SHV 1 76.8 kb >512 32 32
SH12G1019-C* blaCTX–M–64 1 76.8 kb Y ORF-477 64 8 4
SH10G391 blaCTX–M–123, TEM 1 104.5 ∼ 138.9 kb 512 64 32
SH10G391-C* blaCTX–M–123 1 104.5 ∼ 138.9 kb I1 ISEcp1 ORF-477 128 8 8
SH12G1276 blaCTX–M–55 1 138.9 kb 128 2 32
SH12G1276-C* blaCTX–M–55 1 138.9 kb - ISEcp1 IS903 16 0.5 4

∗Isolates labeled with the ending “-C” are transconjugants of the respective donor strains.