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. 2020 Mar 18;12(2):519–539. doi: 10.1007/s12551-020-00680-x

Table 1.

List of relevant abbreviations by section

The formation and regulation of membrane-less cellular organelles pp. 2
  Abbreviation Full description
    IDR Intrinsically disordered region
    LC domain Low-complexity domain
    LLPS Liquid-liquid phase separation
    P-body Processing body
    PML Body Promyoelocytic leukemia body
    rRNA Ribosomal RNA
Stress granule assembly, regulation, and diseases pp. 2–4
  Abbreviation Full description
    ALS Amyotrophic lateral sclerosis
    C9orf72 Chromosome 9 open reading frame 72
    cNLS Canonical NLS
   FG-repeats Phenylalanine-Glycine repeats
    FUS Fused in sarcoma
    G3BP1 G3BP stress granule assembly factor 1 or GTPase-activating protein (SH3 domain)-binding protein 1
    GA Glycine-Alanine
    GP Glycine-Proline
    GR Glycine-Arginine
    hnRNPA1 Heterogeneous nuclear ribonucleoprotein A1
    HRE Hexanucleotide repeat expansion
    HSP70 Heat shock protein 70
    Impα/β Importinα/β
    Kapβ Karyopherinβ
    Kapβ2 Karyopherinβ2
    MBP Maltose-binding protein
    NIR Nuclear import receptor
    NLS Nuclear localization signal
    PA Proline-Alanine
    PR Proline-Arginine
    PY-NLS Proline-tyrosine NLS
    RBP RNA-binding protein
    SG Stress granule
    TDP-43 Transactive response DNA-binding protein of 43 kDa
A new view of chromatin behavior pp. 4–5
  Abbreviation Full description
    BRD4 Bromodomain-containing protein 4
Modulating chromatin structure—compaction and decompaction pp. 5
  Abbreviation Full description
    C-terminal Carboxy-terminal or COOH-terminal
    CD Chromodomain
    CRISPR Clustered regularly interspaced short palindromic repeats
    CSD Chromoshadow domain
    H3K9me3 Trimethylation of histone H3 lysine 9
    Hi-C High-throughput chromosome conformation capture
    hnRNPs Heterogeneous nuclear ribonucleoproteins
    HP1 Heterochromatin protein 1
    SAF-A Scaffold attachment factor A
    Swi6 Chromoshadow domain of the S. pombe HP1 protein
Distinct microenvironment on chromatin pp. 6
  Abbreviation Full description
    CTD C-terminal domain
    EWS Ewing sarcoma breakpoint region 1
    FET family proteins FUS, EWS, and TAF15
    lncRNA Long non-coding RNA
    MED1 Mediator complex subunit 1
    NEAT1 Nuclear Enriched Abundant Transcript 1
    pol II RNA polymerase II
    TAF15 TATA-binding protein-associated factor 2 N
    Tsix The antisense repressor of XIST
    XIST RNA X-inactive specific transcript RNA
Aqueous two-phase systems pp. 7–8
  Abbreviation Full description
    ATPS Aqueous two-phase system
    PEG poly (ethylene) glycol
Polyester microdroplets pp. 8–9
  Abbreviation Full description
    αHA Alpha hydroxy acid
Techniques to observe structure and dynamics of phase-separated proteins pp. 8–9
  Abbreviation Full description
    FRAP Fluorescence recovery after photobleaching
Solution nuclear magnetic resonance (NMR) pp. 9–10
  Abbreviation Full description
    HSQC Heteronuclear single quantum coherence spectroscopy
    NMR Nuclear magnetic resonance
    PCS Pseudocontact shift
    PFG-NMR Pulsed-field gradient-nuclear magnetic resonance
    PRE Paramagnetic relaxation enhancement
    RDC Residual dipolar coupling
    TROSY Transverse relaxation optimized spectroscopy
Electron paramagnetic resonance (EPR) pp. 10
  Abbreviation Full description
    DEER Double electron-electron resonance
    EPR Electron paramagnetic resonance
    SDSL Site-directed spin label
Other biochemical and biophysical methods pp. 10–11
  Abbreviation Full description
    AFM Atomic force microscopy
    Cryo-EM Cryo-electron microscopy
    Micro-ED Micro-electron diffraction
    NAI N-acetylimidazole
    SILAC Stable isotope labeling by/with amino acids in cell culture