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. 2020 May 15;11:696. doi: 10.3389/fphar.2020.00696

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Copyright © 2020 Wang, Bai, Zhang, Ge, Wang, Liang, Li, Gu, Li, Xu, Yang, Xu, Geng and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PUN inhibited ovariectomized induced bone loss. (A) Micro-CT reconstruction images, (B) Bone mineral density (BMD, mg/cm³), (C) Bone volume (BV, mm³), (D) Bone volume/tissue volume (BV/TV, %), (E) Connectivity density (Conn.Dn, 1/mm³), (F) Trabecular number (Tb.N, 1/mm), (G) Trabecular separation (Tb.Sp, mm),(H) Trabecular thickness (Tb.Th, mm). *p < 0.05, **p < 0.01 compared with the OVX group, n = 5 per group. NS, not statistically significant.