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. 2020 May 15;11:249. doi: 10.3389/fendo.2020.00249

Table 4.

Comparison of quality of life in patients with papillary thyroid microcarcinoma who underwent ablation vs. those who underwent surgery.

Ablation group Surgery group p-value Univariate analysis Multivariate analysis
Coef CI p-value Coef CI p-value
SF-36 (THE HIGHER SCORE, THE BETTER QUALITY OF LIFE)
PCS 88.48 ± 8.21 81.18 ± 13.06 0.005* −7.295 [−11.795 to −2.795] 0.002* −8.312 [−13.694 to −2.930] 0.003*
PF 96.57 ± 4.84 94.71 ± 7.17 0.186 −1.868 [−4.412 to 0.676] 0.148 −1.981 [−5.194 to 1.232] 0.224
RP 95.83 ± 10.58 80.88 ± 32.01 0.012* −14.951 [−24.309 to −5.593] 0.002* −22.613 [−33.504 to −11.723] <0.001*
BP 89.42 ± 11.87 83.15 ± 17.09 0.045* −6.270 [−12.407 to −0.132] 0.045* −3.918 [−11.411 to 3.575] 0.301
GH 72.09 ± 19.24 66.00 ± 16.18 0.128 −6.093 [−13.983 to 1.798] 0.128 −5.524 [−15.087 to 4.038] 0.254
MCS 80.92 ± 13.25 80.92 ± 12.08 0.780 −0.787 [−6.363 to 4.788] 0.780 −2.429 [−9.601 to 4.743] 0.502
VT 74.91 ± 15.49 72.79 ± 18.76 0.568 −2.113 [−9.434 to 5.208] 0.568 −2.881 [−12.129 to 6.366] 0.537
SF 90.74 ± 10.29 85.30 ± 14.66 0.044* −5.446 [−10.736 5 to −0.156] 0.044* −3.730 [−10.435 to 2.976] 0.272
RE 92.00 ± 18.24 76.47 ± 37.18 0.029* −15.505 [−27.308 to −3.701] 0.011* −21.901 [−36.737 to −7.064 ] 0.004*
MH 76.00 ± 13.70 70.12 ± 13.58 0.053 −5.882 [−11.826 to 0.061] 0.053 −2.995 [−10.489 to 4.500] 0.429
THYCA-QoL (THE LOWER SCORE, THE BETTER QUALITY OF LIFE)
Neuromuscular 10.70 ± 11.00 12.42 ± 10.15 0.464 1.719 [−2.929 to 6.366] 0.464 0.786 [−4.937 to 6.509] 0.785
Voice 8.02 ± 12.43 5.88 ± 11.52 0.420 −2.142 [−7.404 to 3.119] 0.420 0.070 [−6.577 to 6.716] 0.983
Concentration 5.86 ± 10.81 7.35 ± 13.10 0.564 1.448 [−3.623 to 6.599] 0.564 0.651 [−5.913 to 7.214] 0.844
Sympathetic 13.58 ± 13.76 16.67 ± 15.89 0.337 3.086 [−3.275 to 9.448] 0.337 4.660 [−3.542 to 12.861] 0.262
Throat/mouth 12.96 ± 11.37 15.36 ± 10.95 0.332 2.396 [−2.482 to 7.274] 0.332 2.235 [−4.089 to 8.558] 0.484
Psychological 15.43 ± 13.68 20.83 ± 13.33 0.072 5.401 [−0.495 to 11.297] 0.072 3.439 [−3.912 to 10.790] 0.355
Sensory 13.89 ± 14.01 18.63 ± 14.66 0.133 4.739 [−1.470 to 10.948] 0.133 2.571 [−5.189 to 10.332] 0.512
Problems with scar 5.56 ± 12.54 13.72 ± 20.30 0.022* 8.170 [1.220 to 15.119] 0.022* 10.246 [1.330 to 19.162] 0.025*
Felt chilly 21.60 ± 22.58 25.49 ± 28.50 0.480 3.885 [−7.002 to 14.772] 0.480 1.205 [−12.774 to 15.184] 0.864
Tingling hands/feet 4.32 ± 11.30 5.88 ± 12.90 0.552 1.561 [−3.635 to 6.757] 0.552 −0.012 [−6.651 to 6.626] 0.997
Gained weight 12.34 ± 16.25 19.61 ± 18.56 0.057 7.262 [−0.212 to 14.735] 0.057 5.803 [−3.842 to 15.449] 0.235
Headache 9.88 ± 15.36 12.74 ± 20.12 0.452 2.869 [−4.680 to 10.418] 0.452 4.543 [−5.131 to 14.217] 0.353
Less interest in sex 17.28 ± 21.22 29.41 ± 24.30 0.016* 12.128 [2.357 to 21.899] 0.016* 10.754 [−1.265 to 22.773] 0.079
FoP-Q-SF (THE LOWER SCORE, THE BETTER QUALITY OF LIFE)
Physical health 1.82 ± 0.68 2.00 ± 0.74 0.285 0.165 [−0.140 to 0.471] 0.285 0.145 [−0.227 to 0.518] 0.440
Social family 1.54 ± 0.59 1.72 ± 0.64 0.185 0.177 [−0.086 to 0.441] 0.185 0.108 [−0.224 to 0.439] 0.520
*

p < 0.05.