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. 2020 May 15;7:193. doi: 10.3389/fmed.2020.00193

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Copyright © 2020 Liu, Liao, Zhang, Lin, He, Fang, Tu, Zhao, Wu and Gu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The relationship between significant nodal properties (BC and DC) and pain or fatigue as measured by TBP or FSS(p < 0.05, Bonferroni corrected): (A) BC of node 115 (mPFC) was positively associated with both pain and fatigue; (B) BC of node 208 (INS.L) and DC of nodes 165 (CERE.R) and 172 (FFG.L) were positively associated with fatigue; (C) BC of node 41 (PreCG.R) and DC of node 263 (SPG.L) were positively associated with fatigue. mPFC, medial prefrontal cortex; INS.L, left insula; CERE.R, right cerebellum; FFG.L, left fusiform gyrus; PreCG.R, right precentral cortex; SPG.L, left superior parietal gyrus.