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. 2020 May 15;7:193. doi: 10.3389/fmed.2020.00193

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Copyright © 2020 Liu, Liao, Zhang, Lin, He, Fang, Tu, Zhao, Wu and Gu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The relationship between significant GMV changes and pain or fatigue as measured by TBP or FSS (p < 0.05, Bonferroni corrected): (A) gray matter volume (GMV) of node 230 (PUT.R) was positively associated with both pain and fatigue; (B) GMV of node 41 (PreCG.R) and node 107 (ACC.L) was negatively associated with pain and GMV of node 172 (FFG.L) was positively associated with pain; (C) GMV of nodes 49 (SFG.R) and 263(SPG.L) was negatively associated with fatigue. PUT.R, right putamen; PreCG.R, right precentral cortex; ACC.L, left anterior cingulate cortex; FFG.L, left fusiform gyrus; SFG.R, right superior frontal gyrus; SPG.L, left superior parietal gyrus.