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. 2020 May 15;11:938. doi: 10.3389/fimmu.2020.00938

Figure 2.

Figure 2

Cancer cells recruit myeloid cells to tumor microenvironment (TME) and induce their polarization to immunosuppressive phenotype. Myeloid cells, including macrophages, MDSC, dendritic cells, and neutrophils create tumor-promoting, immunosuppressive TME via multiple factors including reactive oxygen species (ROS), cytokines (IL-10, TGF-β), PD-L1, as well as ARG1. Created with BioRender.