Table 1.
IGFBP7 expression in various tumors.
| Cancer type | Expression status | Test methods | References |
|---|---|---|---|
| Breast | Down-regulation | qRT-PCR | (57, 59) |
| Down-regulation | IHC | (57, 58) | |
| Gastric | Up-regulation | IHC, qRT-PCR | (60, 61) |
| Down-regulation | IHC, qRT-PCR | (62) | |
| Prostate | Down-regulation | Northern blot, ISH | (48, 63) |
| Up-regulation | IHC | (20) | |
| Hepatocellular | Down-regulation | IHC, qRT-PCR | (64) |
| Colorectal | Up-regulation | IHC, Northern blot, ELISA | (65–69) |
| Down-regulation | IHC | (70) | |
| Lung | Down-regulation | IHC, qRT-PCR, Northern blot | (52, 71, 72) |
| Esophageal | Up-regulation | IHC | (73, 74) |
| Melanoma | Down-regulation | IHC | (75) |
| Glioma | Down-regulation | qRT-PCR | (76, 77) |
| Up-reguation | qRT-PCR, Western blot | (78) |
IHC, immunohistochemistry; ISH, in situ hybridization; qRT-PCR, quantitative reverse transcriptase-polymerase chain reaction; ELISA, enzyme-linked immunosorbent assay.