Endophytic fungi |
Fusarium oxysporium |
Vincristine |
Alkaloids |
Anticancer |
– |
Zhang et al., 2000
|
Mycellia sterilia |
Vincristine |
Alkaloids |
Anticancer |
|
Yang et al., 2004
|
Enthrophospora infrequens |
Camptothecin |
Quinolone alkaloid |
Anticancer |
|
Puri et al., 2005
|
Phomopsis cassiae |
3,12-dihydroxydalene 3,12-dihydroxycalamenene 3,11,12-trihydroxycadalene |
Terpenoids |
Anti-proliferative |
HeLa cervical cells |
Silva et al., 2006
|
Periconia atropurpurea |
EtOAc extract |
– |
Cytotoxicity |
– |
Teles et al., 2006
|
Garcinia sp. |
EtOAc extract |
– |
Antiproliferative and cytotoxicity |
Vero cell lines |
Phongpaichit et al., 2007
|
Collentotrichum gloesporiodes |
Taxol |
Alkaloids |
Cytotoxicity |
Human cancer cells lines BT220, int 407, H116, HLK 210, HL251. |
Gangadevi and Muthumary, 2008
|
Aspergillus fumigatus |
Cytotoxic alkaloids |
Alkaloids |
Cytotoxicity |
Leukemia cancer cell line |
Konecny et al., 2009
|
C. gloesporiodes |
Taxol |
Alkaloids |
Anticancer |
|
Nithya and Muthumary, 2009
|
Alternaria alternata |
EtOAc extract |
– |
Antitumor and cytotoxicity |
HeLa cells |
Fernandes et al., 2009
|
Alternaria sp. |
Xanalteric acids |
Phenols |
Cytotoxicity |
|
Kjer et al., 2009
|
Fusarium solani |
Camptothecin |
Quinolone alkaloid |
Anticancer |
– |
Shweta et al., 2010
|
Lasidiplodia theobromae |
Taxol |
Alkaloids |
Anticancer |
MCF-7 |
Pandi et al., 2011
|
Cephalotheca faveolata |
Sclerotiorin |
Polyketides |
Anticancer |
Colon cancer (HCT-116) |
Giridharan et al., 2012
|
Phoma sp. |
5-hydroxyramulosin |
Polyketides |
Anticancer |
|
Santiago et al., 2012
|
Penicillium sp. |
Arisugacin |
Terpenoid derivatives |
Anticancer |
HeLa, HL-60, and K562 cell lines |
Sun et al., 2014
|
A. flavus |
Solamargine |
Steriods |
Cytotoxicity |
– |
El-Hawary et al., 2016
|
Taxomyces andreanae |
Paclitaxel |
Alkaloids |
Anticancer |
– |
Alurappa et al., 2018
|
Chaetomium sp., Alternaria sp., and Collentotrichum sp. |
EtOAc extract |
– |
Cytotoxicity |
HeLa and MCF-7 cells |
Dhayanithy et al., 2019
|
Endophytic actinomycetes |
Streptomyces thermoviolaceus TP-A0648 |
Anicemycin |
Alkaloids |
Antitumor |
– |
Igarashi, 2004
|
Streptomyces sp. SUC1
|
Lansai A-D |
Alkaloids |
Anticancer |
– |
Tuntiwachwuttikul et al., 2008
|
Actinosynnema pretiosum |
Ansamitocin |
Polyketides |
Antitumor |
– |
Siyu-Mao, 2013
|
Micromonospora lupini Lupac 08 |
Lupinacidin C |
Quinones |
Antitumor |
Murine colon carcinoma cells |
Igarashi et al., 2011
|
Streptomyces sp. CS
|
Naphtomycin A |
Quinones |
Antitumor |
P388 and A-549 cell lines |
Lu and Shen, 2007
|
Streptomyces laceyi MS53 |
6-alkalysalicilic acids, salaceyins A and B |
Fatty acid derivatives |
Anticancer |
– |
Singh and Dubey, 2018
|
Endophytic bacteria |
Acinetobacter guillouiae |
EtOAc extract |
– |
Anticancer |
U87MG glioblastoma and A549 lung carcinoma cells |
Sebola et al., 2019
|
Bacillus subtilis PXJ-5, Bacillus sp. CPC3, Bacillus cereus strain ChST
|
Camptothecine |
Alkaloids |
Anticancer |
– |
Shweta et al., 2013
|
– |
EtOAc extract |
– |
Cytotoxic |
A549 lung cancer cell lines |
Swarnalatha and Saha, 2016
|
Pantoea sp. |
EtOAc extract |
– |
Anticancer |
A549 lung carcinoma and UMG87 glioblastoma cell lines |
Uche-Okereafor et al., 2019
|