Figure 1.

RP reduced the level of EB leakage in pre-metastatic microenvironment of lung. The mice were injected with 200 µL of 20 µg/µL EB solution 4 hours before the lung tissue was removed. The lung homogenate was extracted with formamide and the absorbance at a 620 nm was measured. The level of EB leakage in the lung tissue was calculated from the standard curve. Each bar represents mean ± SD (n = 5), and P values were obtained with 1-way ANOVA followed by Dunnett’s post hoc test. *P < .05.