. 2019 Mar 5;18:1534735419827079. doi: 10.1177/1534735419827079

Table 4.

Adjusted Cox Proportional Hazards Model Analysis of Mortality for the Commonly Used TCMs in Patients With Advanced Lung Adenocarcinoma Treated With First-Line EGFR-TKIs in the Study Cohort and the Matched Cohort.

TCM Name	Study Cohort				Matched Cohort
	Adjusted^a				Adjusted^a
	HR	95% CI		P	HR	95% CI		P
Fritillaria thunbergii	0.44	0.26	0.74	.0023	0.37	0.21	0.66	.0007
Oldenlandia diffusa	0.60	0.39	0.92	.0192	0.60	0.38	0.96	.0312
Platycodon grandiflorum	0.24	0.10	0.57	.0014	0.20	0.08	0.50	.0005
Prunus armeniaca	0.52	0.27	1.01	.0542	0.57	0.29	1.13	.1059
Astragalus membranaceus	0.52	0.27	1.01	.0522	0.50	0.25	1.01	.0546
Xiang Sha Liu Jun Zi Tang	0.58	0.31	1.09	.0883	0.61	0.32	1.15	.1244
Xiao Chai Hu Tang	0.47	0.21	1.07	.0707	0.57	0.25	1.29	.1764
Mai Men Dong Tang	0.54	0.27	1.08	.0830	0.62	0.31	1.26	.1852
Sheng Mai San	0.64	0.30	1.35	.2427	0.59	0.26	1.34	.2095
Bai He Gu Jin Tang	0.43	0.22	0.84	.0128	0.29	0.13	0.62	.0015

Abbreviations: EGFR, epidermal growth factor receptor; HR, hazard ratio; TCM, traditional Chinese medicine; TKI, tyrosine kinase inhibitor.

Adjusted for age, sex, insurance income, urbanization, comorbidities, surgery, chemotherapy/radiotherapy, and EGFR-TKI response.