Skip to main content
. 2020 May 15;11:720. doi: 10.3389/fphar.2020.00720

Table 1.

Characteristics of prescriptions including sodium hyaluronate eye drop over time.

2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015
Total prescriptions 39,838 54,539 77,403 98,961 124,346 148,861 168,245 193,632 219,421 230,691 242,299 254,125 267,009 276,537
 Ophthalmology 37,960 (95%) 51,730 (95%) 73,444 (95%) 93,675 (95%) 117,015 (94%) 139,854 (94%) 158,286 (94%) 182,465 (94%) 205,838 (94%) 214,887 (93%) 226,382 (93%) 236,916 (93%) 249,083 (93%) 257,866 (93%)
 Internal medicine 1,022 (3%) 1,218 (2%) 1,945 (3%) 2,626 (3%) 3,731 (3%) 4,624 (3%) 5,110 (3%) 5,827 (3%) 7,171 (3%) 8,217 (4%) 8,246 (3%) 9,134 (4%) 9,495 (4%) 10,168 (4%)
 Others 856 (2%) 1,591 (3%) 2,014 (3%) 2,660 (3%) 3,600 (3%) 4,383 (3%) 4,849 (3%) 5,340 (3%) 6,412 (3%) 7,587 (3%) 7,671 (3%) 8,075 (3%) 8,431 (3%) 8,503 (3%)
Multi-use forms 39,838 (100%) 54,522 (100%) 77,074 (100%) 98,244 (99%) 121,153 (97%) 142,861 (96%) 154,504 (92%) 170,443 (88%) 188,040 (86%) 190,188 (82%) 184,734 (76%) 182,085 (72%) 176,509 (66%) 173,306 (63%)
 Ophthalmology 37,960 (95%) 51,713 (95%) 73,126 (95%) 92,977 (95%) 113,907 (94%) 134,073 (94%) 144,961 (94%) 159,939 (94%) 175,572 (93%) 176,192 (93%) 171,266 (93%) 168,510 (93%) 163,183 (92%) 160,316 (93%)
 Internal medicine 1,022 (3%) 1,218 (2%) 1,940 (3%) 2,616 (3%) 3,679 (3%) 4,543 (3%) 4,907 (3%) 5,466 (3%) 6,620 (4%) 7,420 (4%) 7,092 (4%) 7,159 (4%) 6,962 (4%) 7,138 (4%)
 Others 856 (2%) 1,591 (3%) 2,008 (3%) 2,651 (3%) 3,567 (3%) 4,245 (3%) 4,636 (3%) 5,038 (3%) 5,848 (3%) 6,576 (3%) 6,376 (3%) 6,416 (4%) 6,364 (4%) 5,852 (3%)
Disposable forms 17 (0%) 329 (0%) 717 (1%) 3,193 (3%) 6,000 (4%) 13,741 (8%) 23,189 (12%) 31,381 (14%) 40,503 (18%) 57,565 (24%) 72,040 (28%) 90,500 (34%) 103,231 (37%)
 Ophthalmology 17 (100%) 318 (97%) 698 (97%) 3,108 (97%) 5,781 (96%) 13,325 (97%) 22,526 (97%) 30,266 (96%) 38,695 (96%) 55,116 (96%) 68,406 (95%) 85,900 (95%) 97,550 (94%)
 Internal medicine 5 (2%) 10 (1%) 52 (2%) 81 (1%) 203 (1%) 361 (2%) 551 (2%) 797 (2%) 1,154 (2%) 1,975 (3%) 2,533 (3%) 3,030 (3%)
 Others 6 (2%) 9 (1%) 33 (1%) 138 (2%) 213 (2%) 302 (1%) 564 (2%) 1,011 (2%) 1,295 (2%) 1,659 (2%) 2,067 (2%) 2,651 (3%)
Expenditure (1,000 USD) 143 190 289 397 552 708 870 1,068 1,329 1,528 1,617 1,918 2,278 2,593
 Multi-use forms 143 (100%) 190 (100%) 284 (98%) 382 (96%) 495 (90%) 600 (85%) 661 (76%) 733 (69%) 844 (64%) 872 (57%) 758 (47%) 795 (41%) 848 (37%) 897 (35%)
 Disposable 5 (2%) 15 (4%) 57 (10%) 108 (10%) 209 (24%) 335 (31%) 485 (36%) 656 (43%) 859 (53%) 1,123 (59%) 1,430 (63%) 1,696 (65%)
Estimated market (million USD) 7 10 14 20 28 35 44 53 66 76 81 96 114 130
Total benefits provided by the NHI (million USD) 11,391 12,523 13,691 15,304 17,865 20,479 21,983 24,973 28,163 30,046 31,111 33,218 35,487 38,108
Percent of estimated market 0.06% 0.08% 0.11% 0.13% 0.15% 0.17% 0.20% 0.21% 0.24% 0.25% 0.26% 0.29% 0.32% 0.34%

Total prescriptions are composed of multi-use and disposable forms.

Given the sample size (2% of the total population) of the NHIS-NSC, estimated market size was calculated.

Percent of estimated market was calculated using estimated market and total benefits provided by the NHI (HIRA, 2020).

United States Dollar to South Korean Won exchange rate was assumed to be 1,200.

Results were rounded.