TABLE 1.
Differences in Key Baseline and CPX Variables According to Aerobic Capacity
Variable | Low FIT (n=801) | High FIT (n= 1265) | P value |
---|---|---|---|
Age (y), mean ± SD | 57.5±13.1 | 55.6±14.5 | .003 |
Male sex, No. (%) | 576 (72) | 1050 (83) | <.001 |
BMI, mean ± SD | 29.8±6.6 | 28.0±5.2 | <.001 |
NYHA class, mean ± SD | 2.8±0.74 | 2.2±0.80 | <.001 |
HF ischemic etiology, No. (%) | 352 (44) | 455 (36) | <.001 |
LVEF (%), mean ± SD | 26.0±9.8 | 30.1±10.1 | <.001 |
Prescribed ACE inhibitor, No. (%) | 505 (63) | 759 (60) | .01 |
Prescribed β-blocker, No. (%) | 609 (76) | 834 (66) | <.001 |
Peak RER, mean ± SD | 1.10±0.15 | 1.11±0.13 | .02 |
VE/VCO2 slope, mean ± SD | 39.1±10.9 | 30.9±6.7 | <.001 |
ACE = angiotensin-converting enzyme; BMI = body mass index; CPX = cardiopulmonary exercise testing; FIT = cardiorespiratory fitness (low: <14 mL O2 · kg−1 · min−1; high: ≥14 mL O2 · kg−1 · min−1); HF = heart failure; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association; RER = respiratory exchange ratio; = oxygen consumption; VE/VCO2 = minute ventilation/carbon dioxide production.