Table 2.
Biomarker | Group | Age-adjusted difference in medians (SE) | p |
Aβ38, pg/ml | CAA | Reference group | <0.001 |
AD | 1480 (370) | ||
CS | 1650 (417) | ||
Aβ40, pg/ml | CAA | Reference group | <0.001 |
AD | 3540 (846) | ||
CS | 4060 (954) | ||
Aβ42, pg/ml | CAA | Reference group | <0.001 |
AD | 162 (83.9) | ||
CS | 394 (94.5) | ||
sAβPPα, pg/ml | CAA | Reference group | 0.47 |
AD | 18.9 (16.1) | ||
CS | 20.0 (18.1) | ||
sAβPPβ, pg/ml | CAA | Reference group | 0.024 |
AD | 48.6 (19.1) | ||
CS | 58.8 (21.5) | ||
t-tau, pg/ml | CAA | Reference group | <0.001 |
AD | 357 (115) | ||
CS | –53.1 (129) | ||
p-tau, pg/ml | CAA | Reference group | <0.001 |
AD | 40.9 (12.6) | ||
CS | –2.20 (14.2) | ||
NFL, pg/ml | CAA | Reference group | 0.36 |
AD | –511 (844) | ||
CS | –1310 (952) | ||
sTREM2, pg/ml | CAA | Reference group | 0.55 |
AD | –76.9 (1270) | ||
CS | 1100 (1430) | ||
Neurogranin, pg/ml | CAA | Reference group | 0.021 |
AD | 210 (91.5) | ||
CS | 24.0 (103) |