Table 3.

Motor experiences of daily living as assessed with the MDS-UPDRS II. MDS-UPDRS II = Movement Disorders Society Unified Parkinson’s Disease Rating Scale part II

Item	Fox Insight	Early Fox Insight	PPMI	PDBP	Sig. diff	Post-hoc effect sizes
MDS-UPDRS II Total	12.11 (8.26) (0–52)	9.15 (6.76) (0–46)	5.9 (4.19) (0–22)	11.59 (8.43) (0–46)	*	Early FI vs. PPMI: 0.496
2.1 Speech	58.48% (7400/12654)	46.88% (1909/4072)	33.89% (143/422)	55.86% (391/700)	*	Early FI vs. PPMI: 0.075
2.2 Saliva and Drooling	51.36% (6499/12654)	42.98% (1750/4072)	36.49% (154/422)	49.43% (346/700)
2.3 Chewing and Swallowing	35.43% (4483/12654)	26.94% (1097/4072)	13.03% (55/422)	31.43% (220/700)	*	Early FI vs. PPMI: 0.092
2.4 Eating Tasks	48.01% (6075/12654)	39% (1588/4072)	28.2% (119/422)	44.86% (314/700)	*	Early FI vs. PPMI: 0.063
2.5 Dressing	60.76% (7689/12654)	48.5% (1975/4072)	40.52% (171/422)	58.29% (408/700)
2.6 Hygiene	43.24% (5471/12654)	32.93% (1341/4072)	25.59% (108/422)	38% (266/700)
2.7 Handwriting	70.82% (8961/12654)	61.47% (2503/4072)	61.85% (261/422)	68% (476/700)
2.8 Doing Hobbies and	62.93% (7963/12654)	50.98% (2076/4072)	36.73% (155/422)	58.43% (409/700)	*	Early FI vs. PPMI: 0.082
Other Activities
2.9 Turning in Bed	62.67% (7930/12654)	47.22% (1923/4072)	25.59% (108/422)	55.65% (389/699)	*	Early FI vs. PPMI: 0.126
2.10 Tremor	79.71% (10086/12654)	81.34% (3312/4072)	86.02% (363/422)	78.57% (550/700)
2.11 Getting Out of Bed,	71.13% (9001/12654)	61.71% (2513/4072)	38.63% (163/422)	67.71% (474/700)	*	Early FI vs. PPMI: 0.136
a Car, or a Deep Chair
2.12 Walking and Balance	69.57% (8804/12654)	59.45% (2421/4072)	36.73% (155/422)	64.09% (448/699)	*	Early FI vs. PPMI: 0.133
2.13 Freezing	31.28% (3958/12654)	19.28% (785/4072)	4.74% (20/422)	32.71% (229/700)	*	Early FI vs. PPMI: 0.11