Table 1.

Summary of included studies by type of PRS

Correlates/Outcomes	N Studies	N Threshold PRS Studies	N GWAS Significant PRS Studies
AD risk prediction	15	5	10
MCI risk prediction or MCI conversion	4	2	2
MRI phenotypes	12	7	5
Cognition	21	5	16
CSF biomarkers	8	3	5
Other diseases/syndromes	4	2	2
Disease pathways	3	1	2

AD, Alzheimer’s disease; MCI, mild cognitive impairment; MRI, magnetic resonance imaging; CSF, cerebrospinal fluid; GWAS, genome-wide association study.