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Metabolic effects of the GHSR-A203E mutation in older mice. (A) Body weights of male mice aged 21–66 weeks of age (n = 7–10). (B) Body lengths of male mice at 3 different ages (n = 7–9). (C) Femur lengths of male mice at 65–66 weeks of age (n = 6–8). Data were analyzed by (A–B) repeated measures 2-way ANOVA followed by Sidak's multiple comparison post hoc analysis or by (C) an unpaired Student's t-test. ∗P < 0.05, ∗∗∗∗P < 0.0001.
