Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 22;11(5):390. doi: 10.1038/s41419-020-2544-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a Representative images of mice kidney sections from control and diabetic mice with Oil Red O staining. Scale bars, 50 μm. b Quantification of Oil Red O-positive area in kidney samples from control (n = 5) and diabetic mice (n = 6). **p < 0.01 compared with control. c Relative mRNA levels of genes related to FAO (Pparα, Cpt1α, and Acadl) in control samples and samples from diabetic mice. ** p < 0.01 compared with control. d Western blot analysis of proteins related to FAO and relative protein expression levels in control samples and samples from diabetic mice. **p < 0.01 compared with control. e Representative images of mouse kidney sections from control and diabetes with immunostaining for PPARα and CPT1α. Scale bars, 50 μm. f Relative mRNA levels of genes related to glucose utilization in control samples and samples from diabetic mice. *p < 0.05 compared with control. **p < 0.01 compared with control. g Western blot analysis of proteins related to glucose utilization and relative protein expression levels in control samples and samples from diabetic mice. *p < 0.05 compared with control. **p < 0.01 compared with control. h Representative images of mouse kidney sections from control and diabetes with immunostaining for HK2 and p-LDH. Scale bars, 50 μm. i Quantification of lactate in kidney tissue samples from control and diabetic mice. **p < 0.01 compared with control.