Table 1.
Background and clinical characteristics of the study participants and its relation to hypothyroidism (n = 209).
| Characteristic | Total | Euthyroid | Hypothyroidism (high TSH) | P value |
|---|---|---|---|---|
| Age in years∗1 | 60 (21) | 59 (21) | 60 (15) | 0.599 |
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| Gender %(n) | ||||
| Male | 64.1% (134) | 66.1% (113) | 52.9% (18) | 0.172 |
|
| ||||
| Duration of dialysis, (mo)∗1 | 36 (54) | 36 (54) | 36 (63) | 0.597 |
|
| ||||
| Weight, kg∗1 | 74 (24) | 74.5 (23.3) | 23.3 (32.4) | 0.611 |
|
| ||||
| Comorbidities, % (n) | ||||
| Diabetes | 56.5% (118) | 55% (77) | 61.8% (34) | 0.571 |
| Hypertension | 80.4% (168) | 80.1% (137) | 82.4% (28) | 0.488 |
| Cardiovascular disease | 52.2% (109) | 52.5% (88) | 55.9% (19) | 0.709 |
| Heart failure | 27.3% (57) | 34.4% (44) | 43.3% (13) | 0.401 |
| IHD | 32.1% (67) | 39.6% (55) | 37% (10) | 1 |
| Smoker | 25.4% (53) | 28.7% (49) | 8.8% (3) | 0.017 |
|
| ||||
| Laboratory tests∗ | ||||
| Albumin, serum (g/dL) | 3.83 (0.46) | 3.83 (44) | 3.84 (61) | 0.654 |
| Creatinine, serum (mg/dL) | 8.19 (3.32) | 8.35 (3.55) | 7.12 (3.53) | 0.018 |
| Ferritin (ng/ml) | 545.4 (397) | 538.8 (413.80) | 642.25 (369) | 0.384 |
| Hemoglobin (g/dL) | 10.94 (1.66) | 11 (1.58) | 10.47 (1.86) | 0.109 |
| Ca, serum# (mg/dL) | 9.16 (0.88) | 9.18 (0.92) | 9.17 (0.77) | 0.607 |
| Bicarbonate (mEq/L) | 20.3 (3.5) | 20.5 (3.4) | 19.4 (4.3) | 0.077 |
| P, serum (mg/dL) | 4.44 (1.89) | 4.44 (1.88) | 4.49 (2.56) | 0.843 |
| PTH, (pg/mL) | 309.9 (353.8) | 304.4 (379.87) | 340.65 (222.4) | 0.543 |
| BUN, serum (mg/dL) | 52.3 (15.0) | 52.05 (13.78) | 55.3 (19.13) | 0.939 |
| Potassium (mEq/L) | 5.06 (1.05) | 5.06 (1.07) | 5.14 (84) | 0.750 |
| Sodium (mEq/L) | 138 (4.0) | 138 (4) | 138.5 (3) | 0.380 |
| Chloride (mg/dl) | 97.80 (4.5) | 97.4 (4.74) | 98.1 (3.15) | 0.307 |
∗1Median (interquartile range). #Corrected for albumin; P, phosphate; PTH, parathyroid hormone; Ca, calcium; BUN, blood urea nitrogen; IHD, ischemic heart disease.