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. 2020 May 15;8:456. doi: 10.3389/fbioe.2020.00456

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Copyright © 2020 McCormick, Pearce, Kaye and Haneef.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Resazurin assay of ARPE-19 cells plated on membranes with PLGA or PGA nanoparticles decorated on the basal side showed significantly higher metabolism compared to membrane only controls for the first 14 days of culture. There was no significant difference in metabolism of the cells thereafter up to 1 month or compared with coverslip control. Significant difference *p < 0.05 compared with membrane control, one-way ANOVA followed by Bonferroni post-test (n = 4). Data presented: mean (+/− standard error).