Table 3.
Selection of different (radio)nuclides related to atomic in vivo nanogenerators 225Ac and 227Th and their affinity to various organs.
| Element | Radioisotope | Targeted Organ | Reference |
|---|---|---|---|
| Actinium | 225Ac | liver, bone, kidney | [62] |
| Francium | 221Fr | kidney | [63] |
| Bismuth | 211Bi and 213Bi | kidney | [64,65] |
| Lead | 209Pb and 211Pb | liver, bone, kidney | [66] |
| Polonium | 211Po * and 213Po | liver, kidney, red bone marrow, spleen | [67] |
| Thorium | 227Th | liver, bone, spleen | [68] |
| Radium | 223Ra | bone, soft tissue, intestine | [69,70,71] |
| Astatine | 217At $ | thyroid, stomach, lung | [72,73] |
| Thallium | 207Tl and 209Tl # | heart, kidney, large bowel, thyroid, testicles | [74] |
* Probability of only ≈0.3% in the decay chain of 227Th; $ With a half-life of only 32 msec, the accumulation of 217At could not be proven in these organs but is assumed to be similar to that of other astatine isotopes; # Probability of only ≈2% in the decay chain of 225Ac.