Table 2.
Highest degree of abnormality on CUS | |||||||
---|---|---|---|---|---|---|---|
No abnormalities (N=1,502) | Unilateral or bilateral grade I IVH (N=174) | Unilateral or bilateral grade II IVH (N=157) | Unilateral or bilateral grade III/IV IVH (N=212) | Ventriculo-megaly (N=92) | Unilateral or bilateral cystic PVL or porencephalic cyst (N=169) | Test for linear trend | |
N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | p-value | |
Minor motor function abnormalities | |||||||
Any minor motor finding | 732 (49) | 79 (45) | 84 (54) | 127 (60)* | 59 (64)* | 113 (67)* | <0.001 |
GMFCS level 1 | 62 (4) | 6 (3) | 10 (6) | 26 (12)* | 14 (15)* | 22 (13)* | <0.001 |
Bayley-3 minor motor delay# | 629 (42) | 53 (33)* | 66 (42) | 92 (43) | 48 (52) | 76 (45) | 0.145 |
Fine motor scaled score (mean ± SD) | 8.9 (2.7) | 9.0 (3.0)* | 8.3 (3.1) | 7.7 (3.1) | 8.2 (2.9)* | 7.2 (3.4)* | 0.036 |
Gross motor scaled score (mean ± SD) | 7.9 (2.5) | 7.6 (2.6) | 7.1 (2.7)* | 6.4 (3.3)* | 6.7 (2.9)* | 5.2 (3.4)* | 0.004 |
Axial tone | 49 (3) | 7 (4) | 14 (9)* | 21 (10)* | 11 (12)* | 29 (17)* | <0.001 |
Gait/lower extremity function | 172 (11) | 30 (17)* | 18 (11) | 27 (13) | 12 (13) | 34 (20)* | 0.009 |
Upper extremity function | 37 (2) | 12 (7)* | 10 (6)* | 22 (10)* | 5 (5) | 46 (27)* | <0.001 |
Any major motor function abnormality | 204 (14) | 30 (17) | 30 (19) | 76 (36)* | 33 (36)* | 99 (59)* | <0.001 |
p-value <0.05 as compared to infants with no abnormalities (column 1), based on chi-square tests for categorical variables and t-tests for continuous variables.
Any og motor composite score 71–85, fine motor scaled score 5–7 or gross motor scaled score 5–7.