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. 2019 Aug 9;116(7):1323–1334. doi: 10.1093/cvr/cvz215

Figure 7.

Figure 7

MiR-26b-5p and miR-140-3p alleviate the pro-hypertrophy effect of circRNA_000203 on NMVCs. (A) Morphologies of Ang-II-treated NMVCs after transfection with miR-26b-5p, miR-140-3p, and Gata4 siRNA as revealed by FITC-phalloidin staining assay, respectively. ANP, β-MHC and GATA4 protein expression in NMVCs was assessed by western blot assay (B, D). Data are shown as mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001 (ANOVA with post hoc tests, as indicated). N = 5. (C) Morphologies of circRNA_000203-modified NMVCs after transfection with miR-26b-5p, miR-140-3p, and Gata4 siRNA as revealed by FITC-phalloidin staining assay, respectively. The scale bar is 50 μm. Data are shown as mean ± SEM, *P < 0.05, **P < 0.01 (ANOVA with post hoc tests, as indicated). N = 5.