Table 1.
Stearoyl-CoA desaturase-1 (SCD1), Delta-5-desaturase (D5D) and Delta-6-desaturase (D6D) with purpose, precursor, product and estimated desaturase activity
Desaturase enzyme name | Purpose | Precursor | Product | Estimated desaturase activity |
---|---|---|---|---|
SCD1 | Desaturation of monounsaturated fatty acids from saturated fatty acids | |||
SCD16 | C16:0 (palmitic acid) | C16:1n7 (palmitoleic acid) | 16:1n7/16:0 | |
SCD18 | C18:0 (stearic acid) | C18:1n9 (oleic acid) | 18:1n9/18:0 | |
D6D | Desaturation of polyunsaturated fatty acids (PUFAs) | C18:2n6 (linoleic acid) | C18:3n6 (γ-linolenic acid) | 18:3n6/18:2n6 |
D5D | Desaturation of polyunsaturated fatty acids (PUFAs) | C20:3n6 (dihomo-γ-linolenic acid) | C20:4n6 (arachidonic acid) | 20:4n6/20:3n6 |