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. 2020 May 21;18:100. doi: 10.1186/s12957-020-01865-0

Table 3.

Estimation of total extent for all modalities and compared to histopathology

Method Total extent (mm) Difference from histopathology1 (mm) LOA2 (mm)
CEM Mean (SD) 33.8 (28.3) − 1.4 (18.5) − 37.523; 34.812
Median (Q1; Q3) 22 (14; 50) 0 (− 12; 5)
Min; max 03; 100 − 55; 50
Ultrasound Mean (SD) 26.8 (24.2) − 8.4 (24.3) − 55.977; 39.266
Median (Q1; Q3) 18 (9; 35) − 8 (− 22; − 1)
Min; max 03; 95 − 60; 80
Mammography Mean (SD) 31.0 (24.8) − 4.2 (26.2) − 55.534; 47.179
Median (Q1; Q3) 20 (12; 50) − 5 (− 15; 3)
Min; max 03; 95 − 70; 80
Histopathology Mean (SD) 35.1 (25.4)
Median (Q1; Q3) 26 (15; 45)
Min; max 8; 110

Difference is calculated as follows: Total extent from estimation method − total extent from histopathology

CEM contrast-enhanced mammography

1Bland-Altman statistics (for plots, see Fig. 2)

2Limits of agreement: mean diff ± 1.96 × SD

3Value of 0 was given for lesions that were not detected by the imaging modality