Table 2.

Multiple functions of noncoding RNAs in m⁶A mRNA modification

ncRNAs	Mechanism	Molecule	Biological function	Ref.
miRNAs	Regulate m6A formation on mRNAs	METTL3	Promote cell reprogramming to pluripotency	[85]
GATA3-AS	Promote KIAA1429-GATA3 pre-mRNA interaction	KIAA1429	Promote cell proliferation and metastasis in HCC	[86]
FOXM1-AS	Promote ALKBH5-FOXM1 pre-mRNA interaction	ALKBH5	Promote GSC proliferation and tumorigenesis	[87]
GAS5-AS1	Increase GAS5 stability by interacting with ALKBH5	ALKBH5	Suppress cell proliferation and metastasis in cervical cancer	[88]
miR-33a	Inhibit METTL3 expression by targeting its mRNA	METTL3	Suppress cell proliferation in NSCLC	[90]
miR-4429	Inhibit METTL3 expression by targeting its mRNA	METTL3	Suppress cell proliferation in gastric cancer	[91]
Let-7 g	Inhibit METTL3 expression by targeting its mRNA	METTL3	Suppress cell proliferation in breast cancer	[92]
miR-145	Inhibit YTHDF2 expression by targeting its mRNA	YTHDF2	Suppress cell proliferation in HCC	[93]
miR-744-5p	Inhibit HNRNPC expression by targeting its mRNA	HNRNPC	Induce ovarian cancer cell death	[94]