Table 1.
Characteristics of the EPIC-Norfolk cohort at enrolment
| Population who did not develop PMR or GCA (n = 25 147) | PMR meeting clinical definition at subsequent diagnosis (n = 395) | PMR meeting classification criteria at subsequent diagnosis (n = 272) | GCA meeting clinical definition at subsequent diagnosis (n = 118) | GCA meeting classification criteria at subsequent diagnosis (n = 76) | |
|---|---|---|---|---|---|
| Age at enrolment, yearsa | 58.9 | 64.5 | 64.6 | 64.6 | 64.6 |
| Female, n (%) | 13 670 (54.4) | 294 (74.4) | 204 (75.0) | 88 (74.6) | 57 (75.0) |
| Never smoker, n (%) | 11 443 (45.5) | 197 (49.9) | 139 (51.7) | 47 (39.8) | 30 (41.1) |
| High BPb, n (%) | 3570 (14.2) | 78 (19.8) | 52 (19.2) | 23 (19.5) | 19 (25.0) |
| Systolic BP (s.d.), mmHg | 135 (18) | 140 (20) | 140 (20) | 135 (16) | 136 (17) |
| Diastolic BP (s.d.), mmHg | 83 (11) | 84 (12) | 84 (12) | 82 (11) | 82 (11) |
| Diabetesb, n (%) | 581 (2.3) | 7 (1.8) | 5 (1.8) | 2 (1.7) | 2 (2.6) |
| BMI (s.d.), kg/m2 | 26.4 (3.9) | 26.7 (3.9) | 26.3 (3.6) | 26.0 (3.7) | 25.7 (3.5) |
| Triglycerides (mmol/l)a | 1.5 | 1.6 | 1.6 | 1.6 | 1.6 |
| HDL (s.d.), mmol/l | 1.42 (0.43) | 1.49 (0.42) | 1.48 (0.40) | 1.47 (0.42) | 1.47 (0.38) |
| LDL (s.d.), mmol/l | 3.96 (1.03) | 4.30 (1.16) | 4.30 (1.13) | 4.21 (1.09) | 4.23 (0.96) |
| hs-CRP (s.d.), mg/l | 3.1 (6.3) | 3.8 (7.4) | 3.8 (7.6) | 3.7 (6.0) | 4.3 (7.1) |
a
Medians; otherwise arithmetic means and s.d. are presented.
b
Self-reported at baseline questionnaire. Self-reported diagnoses are from baseline questionnaire at time of recruitment. BP: blood pressure; HDL: high-density lipoprotein; LDL: low-density lipoprotein.