Table 2.
Vascular risk factors and their association to incident diagnoses of PMR and GCA
| PMR | PMR classification set | GCA | GCA classification set | |
|---|---|---|---|---|
| Total (n) | 395 | 272 | 118 | 76 |
| Age | 1.11 (1.09, 1.13); P≤0.0001 | 1.11 (1.09, 1.13); P≤0.0001 | 1.12 (1.09, 1.15); P≤0.0001 | 1.11 (1.07, 1.15); P≤0.0001 |
| Sex (female) | 2.11 (1.55, 2.87); P≤0.0001 | 2.14 (1.55, 2.30); P≤0.0001 | 2.04 (1.23, 3.40); P=0.006 | 1.94 (1.03, 3.67); P=0.041 |
| Ever smoking | 1.13 (0.87, 1.47); P=0.373 | 1.11 (0.84, 1.46); P=0.466 | 2.01 (1.26, 3.20); P=0.003 | 1.81 (1.02, 3.24); P=0.044 |
| BMI | ||||
| <18.5 kg/m2 | Ref | Ref | Ref | Ref |
| 18.5–24.9 kg/m2 | 0.74 (0.34, 1.60); P=0.441 | 0.71 (0.33, 1.55); P=0.394 | 2.04 (0.28, 15.03); P=0.482 | 1.61 (0.22, 11.99); P=0.643 |
| 25.0–29.9 kg/m2 | 0.83 (0.39, 1.79); P=0.637 | 0.76 (0.35, 1.64); P=0.487 | 2.22 (0.31, 16.14); P=0.431 | 1.10 (0.15, 8.20); P=0.923 |
| >30 kg/m2 | 0.67 (0.29, 1.50); P=0.316 | 0.58 (0.25, 1.34); P=0.206 | 1.04 (0.13, 8.54); P=0.967 | 0.76 (0.09, 6.35); P=0.799 |
| Diastolic BP >90 mmHg | 1.35 (1.01, 1.80); P=0.045 | 1.39 (1.03, 1.88); P=0.033 | 0.93 (0.54, 1.60); P=0.789 | 1.29 (0.69, 2.41); P=0.425 |
| LDL >3 mmol/l | 1.00 (0.67, 1.50); P=0.998 | 1.02 (0.67, 1.54); P=0.945 | 1.07 (0.53, 2.16); P=0.860 | 2.29 (0.71, 7.44); P=0.167 |
| hs-CRP bands | ||||
| <1 mg/l | Ref | Ref | Ref | Ref |
| 1 to <3 mg/l | 1.31 (0.93, 1.83); P=0.122 | 1.21 (0.86, 1.71); P=0.269 | 0.71 (0.40, 1.24); P=0.227 | 0.65 (0.30, 1.41); P=0.279 |
| >3 mg/l | 1.45 (1.00, 2.10); P=0.049 | 1.33 (0.91, 1.94); P=0.143 | 1.29 (0.73, 2.28); P=0.378 | 1.93 (0.96, 3.88); P=0.067 |
Data are presented as hazard ratio (95% CI) with P-values. BP: blood pressure; hs-CRP: high-sensitivity CRP; LDL: low-density lipoprotein.