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. 2020 May 15;11:914. doi: 10.3389/fmicb.2020.00914

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Copyright © 2020 Nickels, Poudel, Chatterjee, Farmer, Cordner, Campagna, Giannone, Hettich, Myles, Standaert, Katsaras and Elkins.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pathway for lipid biosynthesis, annotated with statistically significant changes in protein expression upon the use of cerulenin and exogenous FAs to label the cell membrane. An increase in the production of PG is observed (see Figure 4), which may be associated with an increase in YpjQ (Sierro et al., 2007) involved in producing PG lipids and decreases in both UgtP and LtaSC which utilize PG lipids to generate lipoteichoic acid (Percy and Gründling, 2014). For locus tag, UniProt Description, log2 change in expression, and p-values for each differentially expressed protein (see Supplementary Table S2).