FIGURE 5.

Gene description and heatmap of 18 improperly up-regulated genes. When comparing wild-type mycelia to spherules, these genes are significantly down-regulated. (A) Table showing gene descriptions, some of which are involved with chitin remodeling, mating pheromones/quorum sensing, and programmed cell death. When genes were annotated as hypothetical the asterisk (*) indicates ortholog function in other fungi. (B) Heatmap visualization in log₁₀FPKM of the opposing expression patterns for wild-type and mutant lifecycles. A darker color indicates increased expression while lighter indicates decreased expression measured in log₁₀ FPKM.