Table 5.
Indicated imaging by disease site
| NET Location | Recommended imaging |
|---|---|
| Gastric Type 1, 2, 3 | Recommend EGD in Types 1–3; consider EUS (for infiltration, nodal assessment); CT or MR staging with Type 3; consider 68Ga-DOTATATE PET for Types 2 and 3 |
| Duodenal | Recommend EGD; consider EUS (for infiltration, nodal assessment); recommend CT or MR abdomen for staging; consider 68Ga-DOTATATE PET |
| Jejuno-Ileal, Appendix, Cecum |
Recommend CT or MR abdomen/pelvis; consider specific enterography or enteroscopy protocols for jejuno-ileal or colonoscopy for cecal; recommend 68Ga-DOTATATE PET for staging; consider echocardiogram |
| Distal Colo-Rectal | Recommend CT or MR abdomen/pelvis; recommend colonoscopy; consider EUS for rectal lesions; recommend 68Ga-DOTATATE PET |
| Pancreatic | Recommend CT or MR for staging; consider EGD / EUS for staging / biopsy; recommend 68Ga-DOTATATE PET for staging |
| Poorly differentiated NE carcinoma (NEC) | Recommend CT chest/abdomen/pelvis; Consider 18FDG-PET, 68Ga-DOTATATE PET, Nuclear bone scan |
EGD: esophagogastroduodenoscopy.
Data from Kunz PL, Reidy-Lagunes D, Anthony LB, et al. Consensus guidelines for the management and treatment of neuroendocrine tumors. Pancreas. 2013;42(4):557–577.