Table 3:
Up and down regulated pathways for DEGs
| Pathway Name – Down Regulated | p-value |
|---|---|
| GLI proteins bind promoters of Hh responsive genes to promote transcription | 0.00105 |
| Generic Transcription Pathway | 0.00772 |
| Nitric oxide stimulates guanylate cyclase | 0.00781 |
| Pathway Name – Up Regulated | p-value |
| Signaling by Nuclear Receptors | 0.00013 |
| RNA Polymerase I Chain Elongation | 0.00013 |
| Muscle contraction | 0.00015 |
| mRNA Splicing - Minor Pathway | 0.0002 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | 0.00022 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | 0.00027 |
| Dual incision in TC-NER | 0.0003 |
| NoRC negatively regulates rRNA expression | 0.00055 |
| RA biosynthesis pathway | 0.00064 |
| 0.0007 | |
| RNA Polymerase I Promoter Clearance | 0.00075 |
| RHO GTPases activate PKNs | 0.00081 |
| RNA Polymerase I Transcription | 0.00088 |
| Nucleotide Excision Repair | 0.00088 |
| Cardiac conduction | 0.00089 |
| Telomere Maintenance | 0.00119 |
| CLEC7A (Dectin-1) signaling | 0.00147 |
| Dual Incision in GG-NER | 0.00168 |
| Transcriptional regulation by small RNAs | 0.00188 |
| Formation of TC-NER Pre-Incision Complex | 0.00201 |
| B-WICH complex positively regulates rRNA expression | 0.00263 |
| Senescence-Associated Secretory Phenotype (SASP) | 0.00265 |
| Chromosome Maintenance | 0.00265 |
| Signaling by Retinoic Acid | 0.00273 |