Table 3.

Odds ratios (ORs) of slow gait speed^a associated with the groups of low 25(OH)D^b (yes vs. no) and high IL-6^c (yes vs. no) in Model 1 and low IGF-1^d (yes vs. no) and high IL-6 (yes vs. no) in Model 2 adjusted for potential confounders^e

Model 1: Joint effects of low 25(OH)D (yes vs. no) and high IL-6 (yes vs. no)			Model 2: Joint effects of low IGF-1 (yes vs. no) and high IL-6 (yes vs. no)
Group	OR (95% CI)	p	Group	OR (95% CI)	p
Yes, Yes	1.63 (1.15, 2.32)	.006	Yes, Yes	1.65 (1.19, 2.29)	.003
No, Yes	1.12 (0.80, 1.56)	.50	No, Yes	1.07 (0.75, 1.53)	.72
Yes, No	0.89 (0.60, 1.30)	.54	Yes, No	0.91 (0.65, 1.27)	.57
No, No	Reference group		No, No	Reference group
Follow-upf			Follow-upf
3-year	1.59 (1.20, 2.12)	.001	3-year	1.51 (1.18, 1.93)	.001
6-year	1.32 (0.99, 1.77)	.06	6-year	1.28 (0.97, 1.69)	.08

Note: CI = Confidence interval; CRP = C-reactive protein; IGF-1 = Insulin-like growth factor 1; 25(OH)D = 25-hydroxy vitamin D; IL-6 = Interleukin 6.

^a,b,c,dTime-dependent variables.

^a<0.8 m/s;

^b<20 ng/mL;

^c≥2.87 pg/mL;

^d<112 ng/mL;

^eIncluding demographic covariates, diseases, physical activity, daily vitamin D intake (µg; model 1), and body mass index;

^fVisit time (reference = baseline visit).