Table 1.

Hazard Ratios for CRC Mortality and Baseline NSAID Use.¹⁹

Categories	Any NSAID			Aspirin				Non-aspirin NSAID
	Total/events	HR	95% CI	Categories	Total/events	HR	95% CI	Categories	Total/events	HR	95% CI
Duration of use in years
None		1	Reference	None		1	Reference	None		1	Reference
<1 y	12 605/43	1.12	0.80-1.56	<1 y	5163/16	0.92	0.54-1.57	<6 mo	5250/19	1.37	0.86-2.17
1 to 3 y	15 757/57	1.06	0.78-1.44	1 to 3 y	8738/39	1.27	0.89-1.81	0.5 to 2	5811/19	1.01	0.61-1.67
3 to 6 y	13 834/34	0.82	0.57-1.17	3 to 9 y	9760/27	0.87	0.58-1.29	2 to 5	7198/16	0.78	0.47-1.31
6+ y	14 847/39	0.75	0.52-1.08	9+ y	7944/19	0.59	0.34-1.00	5+ y	7179/18	0.89	0.55-1.45
P trend = .12
Strength in milligrams
None					None	1	Reference	None
<200 mg	10 466/31	0.84	0.56-1.25	<81 mg	421/1	—	—	<200 mg	3296/6	0.64	0.29-1.44
200-324.9 mg	13 719/50	1.29	0.95-1.75	81 mg	6563/23	0.97	0.62-1.53	200 mg	10 070/37	1.34	0.95-1.90
325 mg	20 180/66	0.95	0.71-1.26	325 mg	20 173/66	0.96	0.72-1.26	201-500 mg	7691/18	0.80	0.49-1.31
>325 mg	12 678/26	0.61	0.39-0.94	>325 mg	3134/6	0.52	0.22-1.27	>500 mg	438/11	0.78	0.40-1.51
P trend = .20

Note. CRC = colorectal cancer; NSAID = nonsteroidal anti-inflammatory drugs; HR = hazard ratio; CI = confidence interval.