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. 2020 May 21;26(19):2333–2348. doi: 10.3748/wjg.v26.i19.2333

Table 4.

Therapeutic strategies

Mild gastroparesis Moderate gastroparesis Severe gastroparesis
Diet and nutritional support Adequate oral nutrition Disturbed oral nutrition Compromized oral nutrition
Small frequent meals; Low fat, low fibre; Glycemic control in diabetics Small, frequent meals; Low fat, low fibre; Glycemic control in diabetics; Caloric liquids; Artificial nutrition rarely required Liquid nutrient supplements; Nutrition by PEG-J
Prokinetics Metroclopramide; Domperidone; Levosulpiride Metroclopramide; Domperidone; Levosulpiride 1Metroclopramide; Domperidone; 1Levosulpiride; 1Erytromycin; Prucalopride
Antiemetics and symptom modulators Rarely needed Ondansetron 1Ondansetron; Triciclic antidepressant; Cannabinoids
Drug-refractory patients
Endoscopic techniques Not needed Not needed Botulin toxin; Transpyloric stenting; Ballon dilatation; G-POEM
Gastric electrostimulation Not needed Not needed Compassionate use
Gastric procedures Not needed Not needed Laparoscopic Pyloroplastic
1

Available for intravenous administration. PEG-J: Percutaneous endoscopic transgastric jejunostomy; G-POEM: Gastric peroral endoscopic myotomy.