Table 2.
Top five results of the four studies selected.
| Gene | Official Full Name | CpGa or DMRb | p-value | Chromosome | References |
|---|---|---|---|---|---|
| ALOX15 | Arachidonate 15-lipoxygenase | 4541333-4541334 | 7.82 x 10−4 | chr 17 | Yang et al. (11) |
| HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1 | 33041220-33041697 | 1.04 x 10 −6 | chr 6 | Yang et al. (11) |
| GJA4 | Gap junction protein alpha 4 | 35258778-35258933 | 6.00 x 10 −3 | chr 1 | Yang et al. (11) |
| POSTN | Periostin | 38172802-38172803 | 7.25 x 10 −4 | chr 13 | Yang et al. (11) |
| LDLRAD3 | Low density lipoprotein receptor class A domain containing 3 | 36030085-36030086 | 6.23 x 10 −6 | chr 11 | Yang et al. (11) |
| OR2B11 | Olfactory receptor family 2 subfamily B member 11 | cg00112952 | 0.004 | chr 1 | Zhang et al. (12) |
| OR2B11 | Olfactory receptor family 2 subfamily B member 11 | cg14830002 | 0.001 | chr 1 | Zhang et al. (12) |
| TET1 | Tet methylcytosine dioxygenase 1 | cg23602092 | 0.016 | chr 10 | Zhang et al. (12) |
| ATP9B | Atpase phospholipid transporting 9B | cg26017880 | 0.018 | chr 18 | Zhang et al. (12) |
| LAMA5 | Laminin subunit alpha 5 | cg14007090 | 0.023 | chr 20 | Zhang et al. (12) |
| METTL1 | Methyltransferase like 1 | cg20372759 | 2.18 × 10−22 | chr 12 | Forno et al. (13) |
| GJA4 | Gap junction protein alpha 4 | cg15006973 | 8.53 × 10−21 | chr 1 | Forno et al. (13) |
| NTRK1 | Neurotrophic receptor tyrosine kinase 1 | cg24707200 | 8.53 × 10−21 | chr 1 | Forno et al. (13) |
| PDE6A | Phosphodiesterase 6A | cg08844313 | 8.53 × 10−21 | chr 5 | Forno et al. (13) |
| FBXL7 | F-box and leucine rich repeat protein 7 | cg00664723 | 8.53 × 10−21 | chr 5 | Forno et al. (13) |
| NOS1AP | Nitric oxide synthase 1 adaptor protein | cg04165922 | 0.013 | chr 1 | Cardenas et al. (14) |
| COPS8 | COP9 signalosome subunit 8 | cg10117579 | 0.013 | chr 2 | Cardenas et al. (14) |
| GLB1 | Galactosidase beta 1 | cg24113459 | 0.013 | chr 3 | Cardenas et al. (14) |
| KCNH2 | Potassium voltage-gated channel subfamily H member 2 | cg22060869 | 0.013 | chr 7 | Cardenas et al. (14) |
| MSI2 | Musashi RNA binding protein 2 | cg04727951 | 0.013 | chr 17 | Cardenas et al. (14) |
The genes highlighted with a light gray background are involved in immunity, the genes highlighted with a dark gray background encode for extracellular matrix, receptor and other membrane proteins. The genes with a white background are involved in other functions.
a
Citosine-phosphate-guanine (CpGs).
b
Differentially methylated region (DMR).