Table 2.
The hub genes in the protein-protein interaction (PPI) network (Degree ≥ 10).
| Gene symbol | Degree |
|---|---|
| MYC | 47 |
| IL6 | 42 |
| TNF | 39 |
| AURKA | 37 |
| CCNB2 | 35 |
| CHEK1 | 34 |
| AURKB | 33 |
| MELK | 30 |
| TTK | 30 |
| TPX2 | 30 |
| KIF2C | 29 |
| UBE2C | 29 |
| CENPA | 29 |
| CDC20 | 29 |
| CDCA8 | 28 |
| OIP5 | 27 |
| FOXM1 | 27 |
| RAD51AP1 | 25 |
| PTTG1 | 25 |
| MCM6 | 25 |
| MCM2 | 25 |
| MCM4 | 25 |
| ESR1 | 24 |
| MCM5 | 23 |
| GART | 21 |
| SHCBP1 | 21 |
| DEPDC1 | 20 |
| JAK2 | 20 |
| CHAF1B | 19 |
| CDCA2 | 18 |
| MYBL2 | 18 |
| MYB | 18 |
| ARHGAP11A | 17 |
| INSR | 17 |
| CDCA7 | 17 |
| KIT | 17 |
| AR | 17 |
| CCNE1 | 16 |
| LMNB1 | 16 |
| MAP3K1 | 15 |
| DEPDC1B | 14 |
| GATA3 | 13 |
| KIFC1 | 12 |
| VCAM1 | 12 |
| LYN | 11 |
| BRCA2 | 11 |
| BMP2 | 11 |
| CCL5 | 11 |
| HIST3H2BB | 10 |
| CXCL9 | 10 |
| CXCL10 | 10 |