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. 2020 May 15;11:485. doi: 10.3389/fgene.2020.00485

FIGURE 2.

FIGURE 2

Upregulation of circRNA_103809 suppresses the proliferation of breast cancer cells in vitro. (A) The expression of circRNA_103809 is downregulated in breast cancer cell lines (MDA-MB-157, MDA-MB-157, MDA-MB-213, MDA-MB-468, T47D, and BT20) compared with a normal breast cell line (MCF-10A). (B) Successful generation of circRNA_103809-overexpressing MDA-MB-157 cells induced by plasmid interference. (C) Successful generation of circRNA_103809-overexpressing MDA-MB-213 cells induced by plasmid interference. (D,E) The effect of upregulation of circRNA_103809 on the proliferation of breast cancer cells in vitro measured using a CCK-8 assay. All experiments were repeated at least three times, *P < 0.05, **P < 0.01, ***P < 0.001.