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. 2020 May 15;11:485. doi: 10.3389/fgene.2020.00485

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Copyright © 2020 Liu, Luo, Dong, Guo, Luo, Ye and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Upregulation of circRNA_103809 inhibits the migration and invasion abilities and regulates the epithelial mesenchymal transition (EMT) process in breast cancer cells. (A) Cell migration and invasion images (left) and statistical analysis (right) of migrated and invaded MDA-MB-157 cells after the overexpression of circRNA_103809. (B) Cell migration and invasion images (left) and statistical analysis (right) of migrated and invaded MDA-MB-213 cells after the overexpression of circRNA_103809. (C) The expression of an epithelial cell marker (E-cadherin) and mesenchymal markers (N-cadherin and vimentin) in MDA-MB-157 and MDA-MB-213 cells detected by western blotting after the overexpression of circRNA_103809. All experiments were repeated at least three times. ***P < 0.001.