Table 2.

Basal and final results and differences between groups (intervention and control).

	Total	Differences per time point			Adjusted difference
		Intervention	Control	p-value	CareWell Effect	p-value
Clinical data
Body Mass Index (BMI)						0.099
N	620	335	285
Basal	29.9 (5.4)	30.4 (5.8)	29.4 (4.9)	0.016	–
Final	29.5 (5.4)	29.9 (5.6)*	28.9 (5)	0.038	–0.3 (–0.8,0.2)
Oxygen saturation (%)						0.639
N	546	261	285
Basal	95.8 (2.4)	95.4 (2.6)	96.2 (2.2)	<0.001	–
Final	96.1 (2.3)	95.9 (2.1)*	96.2 (2.4)	0.114	0.1 (–0.4,0.5)
Blood glucose (mg/dl)						0.677
N	546	261	285
Basal	129.9 (45.9)	131.7 (50.8)	128.3 (41)	0.401	–
Final	118.8 (50)	111 (48.7)*	123.2 (50.3)	0.012	–0.6 (–12.7,11.5)
HbA1c (%)						0.131
N	364	177	187
Basal	6.8 (1)	6.9 (1.1)	6.8 (1)	0.236	–
Final	6.8 (1.2)	6.6 (1.1)	6.8 (1.2)	0.227	–0.4 (–0.8,–0.04)
Creatinine (mg/dl)						0.182
N	364	177	187
Basal	1.1 (0.4)	1.1 (0.5)	1.1 (0.4)	0.252	–
Final	1.2 (0.6)	1.2 (0.6)*	1.1 (0.5)*	0.220	–0.1 (–0.1,0.02)
Geriatric Depression Scale						0.233
N	757	403	354
Basal	3.9 (3.7)	3.9 (3.7)	4 (3.7)	0.607	–
Final	4 (3.8)	3.7 (3.7)	4.2 (3.8)	0.089	–0.6 (–1.6,0.3)
Physical functional status
Barthel index						0.889
N	757	403	354
Basal	87.8 (20.3)	86.7 (22)	89.2 (18.2)	0.085	–
Final	86.7 (21.4)	85.4 (22.9)*	88.1 (19.6)*	0.085	–1.1 (–3.2,1)

Data presented as mean, standard deviation or their corresponding 95% confidence interval; N, sample size used in the analysis (only included pilot sites which has the follow-up for the corresponding parameter); * indicates if there are pre-post differences within each arm (intervention or control); CareWell effect, indicates the difference between the intervention over the control group, by the interaction coefficient between the care group and the follow-up period. The effect coefficient was estimated considering follow-up of 12 months, and the mixed-effect models were adjusted using age, gender, and age-adjusted Charlson Comorbidity Index.